Article
The lack of genotype-phenotype relationship between platelet serotonin concentration and serotonin transporter gene promoter polymorphism in healthy subjects.
Neuroscience letters - 2 Oct 2009
Pivac Nela, Nedic Gordana, Mustapic Maja, Babic Ana, Stipcevic Tamara, Borovecki Fran, Hajnsek Sanja, Muck-Seler Dorotea
Abstract excerpt
A polymorphism in the serotonin transporter gene (5-HTTLPR) is frequently studied for association with antidepressant treatment response, different personality traits, and psychiatric disorders. Baseline platelet serotonin (5-HT) concentration has been proposed to indicate a good or a poor treatment response to antidepressant drugs and to be associated with particular symptoms in psychiatric disorders. The aim of...
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