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Article

Mutation detection by ligation to complete n-mer DNA arrays.

Genome research - 1 Nov 1998

Gunderson K L, Huang X C, Morris M S, Lipshutz R J, Lockhart D J, Chee M S

Abstract excerpt

A new approach to comparative nucleic acid sequence analysis is described that uses the ligation of DNA targets to high-density arrays containing complete sets of covalently attached oligonucleotides of length eight and nine. The combination of enzymatic or chemical ligation with a directed comparative analysis avoids many of the intrinsic difficulties associated with hybridization-based de novo sequence...

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Identifiers

PMID: 9847078
DOI: 10.1101/gr.8.11.1142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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