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Article

Universal DNA microarray method for multiplex detection of low abundance point mutations.

Journal of molecular biology - 17 Sept 1999

Gerry N P, Witowski N E, Day J, Hammer R P, Barany G, Barany F

Abstract excerpt

Cancers arise from the accumulation of multiple mutations in genes regulating cellular growth and differentiation. Identification of such mutations in numerous genes represents a significant challenge in genetic analysis, particularly when the majority of DNA in a tumor sample is from wild-type stroma. To overcome these difficulties, we have developed a new type of DNA microchip that combines polymerase chain...

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PMID: 10493873
DOI: 10.1006/jmbi.1999.3063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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