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Article

Ligase-based detection of mononucleotide repeat sequences.

Nucleic acids research - 15 Dec 1999

Zirvi M, Nakayama T, Newman G, McCaffrey T, Paty P, Barany F

Abstract excerpt

Up to 15% of all colorectal cancers are considered to be replication error positive (RER(+)) and contain mutations at hundreds of thousands of microsatellite repeat sequences. Recently, a number of intragenic mononucleotide repeat sequences have been demonstrated to be targets for inactivating genes in RER(+)colorectal tumors. In this study, thermostable DNA ligases were tested for the ability to detect...

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Identifiers

PMID: 10572192
DOI: 10.1093/nar/27.24.e40
PMCID: PMC148763

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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