Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic characterization of rat hepatoma cell lines and lineage-specific regulation of gene expression by differentiation agents.

Differentiation; research in biological diversity - 1 Aug 1998

Zvibel I, Fiorino A S, Brill S, Reid L M

Abstract excerpt

Hepatoma cell lines can be characterized by their expression of hepatocyte- and biliary-specific genes and by their response to differentiating agents in a lineage-dependent manner. These characteristics can be used to map the maturational lineage position of the cell lines. Tissue-specific gene expression and regulation by heparin, dimethylsulfoxide (DMSO), and sodium butyrate (SB) were examined in three rat...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Cell Differentiation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epithelial Cells

Share to Gene Expression Regulation, Neoplastic

Share to Liver Neoplasms, Experimental

Share to Phenotype

Source

Identifiers

PMID: 9745712
DOI: 10.1111/j.1432-0436.1998.00215.x

Genes

AFP
FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic characterization of rat hepatoma cell lines and lineage-specific regulation of gene expression by differentiation agents.PMID 9745712Read ↗

Quantitative gene expression profiling reveals a fetal hepatic phenotype of murine ES-derived hepatocytes.Semantic proximity Read ↗

Derivation, characterization, and phenotypic variation of hepatic progenitor cell lines isolated from adult rats.Semantic proximity Read ↗

In vitro differentiation of WB-F344 rat liver epithelial cells into the biliary lineage.Semantic proximity Read ↗

Timing and sequence of differentiation of embryonic rat hepatocytes along the biliary epithelial lineage.Semantic proximity Read ↗

Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cellsSemantic proximity Read ↗

Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cellsSemantic proximity Read ↗

CD203c is expressed by human fetal hepatoblasts and distinguishes subsets of hepatoblastomaSemantic proximity Read ↗

Expression of some hepatocyte-like functional properties of WRL-68 cells in cultureSemantic proximity Read ↗

An improved polarized rat hepatoma hybrid cell line: generation and comparison with its hepatoma relatives and hepatocytes in vivoSemantic proximity Read ↗

Long-term culture and characteristics of normal rat liver bile duct epithelial cells.Semantic proximity Read ↗

Expression and induction of a large set of drug‐metabolizing enzymes by the highly differentiated human hepatoma cell line BC2Semantic proximity Read ↗

Isolation, biochemical characterization, long-term culture, and phenotype modulation of oval cells from carcinogen-fed rats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.