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Article

A Candida albicans chaperonin subunit (CaCct8p) as a suppressor of morphogenesis and Ras phenotypes in C. albicans and Saccharomyces cerevisiae.

Microbiology (Reading, England) - 1 Nov 1998

Rademacher Felicitas, Kehren Verena, Stoldt Volker R, Ernst Joachim F

Abstract excerpt

Saccharomyces cerevisiae and the pathogen Candida albicans can be induced to undergo morphogenesis from a yeast to a filamentous form. A C. albicans gene (CaCCT8) was identified encoding a subunit of the Cct chaperonin complex, whose expression prevents filament formation in both fungi without interfering with growth of the yeast form. In S. cerevisiae, pseudohyphal growth induced by Ras2Val19, by overproduction...

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PMID: 9846730
DOI: 10.1099/00221287-144-11-2951

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