Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chs1 of Candida albicans is an essential chitin synthase required for synthesis of the septum and for cell integrity.

Molecular microbiology - 1 Mar 2001

Munro C A, Winter K, Buchan A, Henry K, Becker J M, Brown A J, Bulawa C E, Gow N A

Abstract excerpt

CaCHS1 of the fungal pathogen Candida albicans encodes an essential chitin synthase that is required for septum formation, viability, cell shape and integrity. The CaCHS1 gene was inactivated by first disrupting one allele using the ura-blaster protocol, then placing the remaining allele under the control of the maltose-inducible, glucose-repressible MRP1 promoter. Under repressing conditions, yeast cell growth...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern
Share to Candida albicans

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Candidiasis

Share to Cell Wall

Share to Chitin Synthase

Share to Gene Expression Regulation, Fungal

Share to Mice, Inbred ICR

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 11251855
DOI: 10.1046/j.1365-2958.2001.02347.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chs1 of Candida albicans is an essential chitin synthase required for synthesis of the septum and for cell integrity.PMID 11251855Read ↗

Candida albicans strains deficient in CHS7, a key regulator of chitin synthase III, exhibit morphogenetic alterations and attenuated virulence.Semantic proximity Read ↗

Cell wall protection by the Candida albicans class I chitin synthases.Semantic proximity Read ↗

A hyphal-specific chitin synthase gene (CHS2) is not essential for growth, dimorphism, or virulence of Candida albicans.Semantic proximity Read ↗

Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking β(1,3)-glucan remodeling.Semantic proximity Read ↗

Chitin synthase I and chitin synthase II are not required for chitin synthesis in vivo in Saccharomyces cerevisiae.Semantic proximity Read ↗

The function of chitin synthases 2 and 3 in the Saccharomyces cerevisiae cell cycle.Semantic proximity Read ↗

The chsB gene of Aspergillus nidulans is necessary for normal hyphal growth and development.Semantic proximity Read ↗

An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae.Semantic proximity Read ↗

The chsD and chsE genes of Aspergillus nidulans and their roles in chitin synthesis.Semantic proximity Read ↗

Loss of CHT3 in Candida albicans wild-type strains increases surface-exposed chitin and affects host-pathogen interactionSemantic proximity Read ↗

Attenuated virulence of chitin-deficient mutants of Candida albicans.Semantic proximity Read ↗

The Candida albicans CHS4 gene complements a Saccharomyces cerevisiae skt5/chs4 mutation and is involved in chitin biosynthesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.