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Article

The role of Candida albicans SPT20 in filamentation, biofilm formation and pathogenesis.

PloS one - 1 Jan 2014

Tan Xiaojiang, Fuchs Beth Burgwyn, Wang Yan, Chen Weiping, Yuen Grace J, Chen Rosalyn B, Jayamani Elamparithi, Anastassopoulou Cleo, Pukkila-Worley Read, Coleman Jeffrey J, Mylonakis Eleftherios

Abstract excerpt

Candida albicans is a ubiquitous fungus, which can cause very serious and sometimes life-threatening infections in susceptible patients. We used Caenorhabditis elegans as a model host to screen a library of C. albicans mutants for decreased virulence and identified SPT20 as important for virulence. The transcription co-activator SPT20 was identified originally as a suppressor of Ty and solo δ insertion mutations,...

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Identifiers

PMID: 24732310
DOI: 10.1371/journal.pone.0094468
PMCID: PMC3986095

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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