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[Evaluation of yeast functional assay to detect p53 gene mutation in minute endoscopic samples of colonic mucosal neoplasia].

[Hokkaido igaku zasshi] The Hokkaido journal of medical science - 1 Sept 1998

Nakamura Y

Abstract excerpt

Mutation in the p53 tumor suppressor gene is known to play a critical role in the carcinogenesis of many types of human cancers, especially in colon carcinogenesis. To investigate the early stage of neoplastic processes, a simple and reliable method is needed to evaluate the state of p53 mutation. For this purpose, we tested the availability of the recently developed yeast functional assay to minute endoscopic...

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PMID: 9846280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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