Article
Detection of p53 gene mutations in human esophageal squamous cell carcinomas using a p53 yeast functional assay: possible difference in esophageal carcinogenesis between the young and the elderly group.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2001
Okuda E, Osugi H, Morimura K, Takada N, Takemura M, Fukushima S, Higashino M, Kinoshita H
Abstract excerpt
A p53 yeast functional assay, which cannot only detect p53 gene mutations but also can assess p53 gene function, was used to screen for p53 gene dysfunction in human esophageal squamous cell carcinomas. Surgically resected frozen tissues of esophageal squamous cell carcinomas from 57 patients wer...
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