Article
[Analyses of p53 mutations in breast cancers with a combined use of yeast functional assay and immunohistochemical staining].
[Hokkaido igaku zasshi] The Hokkaido journal of medical science - 1 May 1998
Takahashi M
Abstract excerpt
p53 status was examined in a total of 52 primary breast cancers, using a combination of yeast-based assay for transcriptional activity of p53 (yeast functional assay, YA) and immunohistochemical staining (IHC) for p53 protein accumulation. Results by the two methods were compared, and their correlations to the clinicopathological characteristics were analyzed. Nineteen cases (37%) were shown to have p53 mutations...
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