Article
[Analyses of p53 mutations in breast cancers with a combined use of yeast functional assay and immunohistochemical staining].
[Hokkaido igaku zasshi] The Hokkaido journal of medical science - 1 May 1998
Takahashi M
Abstract excerpt
p53 status was examined in a total of 52 primary breast cancers, using a combination of yeast-based assay for transcriptional activity of p53 (yeast functional assay, YA) and immunohistochemical staining (IHC) for p53 protein accumulation. Results by the two methods were compared, and their corre...
Topics
- Biomarkers, Tumor
- Breast Neoplasms
- DNA Mutational Analysis
- Female
- Humans
- Immunohistochemistry
- Mutation
- Neoplasm Invasiveness
- Prognosis
- Saccharomyces cerevisiae
- Survival Rate
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53
