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Article

Examination of methicillin-resistant and methicillin-susceptible Staphylococcus aureus mutants with low-level fluoroquinolone resistance.

Antimicrobial agents and chemotherapy - 1 Dec 1998

Sulavik M C, Barg N L

Abstract excerpt

For Staphylococcus aureus, stepwise mutations result in high-level quinolone resistance. Methicillin-resistant and -susceptible quinolone-resistant, first-step mutants generated in vitro were obtained and found to be no different than those recovered from murine abscesses. Approximately 10% of all first-step mutants were resistant to ethidium bromide, and selected strains had mutations that mapped to flqB....

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Identifiers

PMID: 9835538
DOI: 10.1128/AAC.42.12.3317
PMCID: PMC106046

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