Article
Characterisation of Salmonella spp. mutants produced by exposure to various fluoroquinolones.
International journal of antimicrobial agents - 1 Aug 2003
Cebrian L, Sirvent E, Rodríguez Díaz Juan Carlos, Ruiz M, Royo G
Abstract excerpt
We repeatedly exposed six Salmonella spp. strains of different serotypes (three susceptible to nalidixic acid and three resistant) to constant low concentrations of various fluoroquinolones with the aim of characterising the mutations that produce the first decrease in susceptibility to these agents. The fluoroquinolone-susceptibility of all the strains was reduced after repeated exposure to these agents....
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