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Article

Susceptibility and resistance genes to fluoroquinolones in methicillin-resistant Staphylococcus aureus isolated in 2002.

International journal of antimicrobial agents - 1 May 2005

Noguchi Norihisa, Okihara Takeshi, Namiki Yuta, Kumaki Yuichi, Yamanaka Yoshihiro, Koyama Masaharu, Wakasugi Kazunori, Sasatsu Masanori

Abstract excerpt

The activity of six fluoroquinolones (FQs) was determined against 100 methicillin-resistant Staphylococcus aureus (MRSA) isolated in 2002 along with mutations in the grlA and gyrA genes and in the norA promoter of these isolates. Of the isolates tested, 97% had mutations in grlA and gyrA. A single mutation in grlA and gyrA resulted in a decrease of susceptibility to old generation FQs (norfloxacin, enoxacin,...

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Identifiers

PMID: 15848290
DOI: 10.1016/j.ijantimicag.2004.11.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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