Article
Expression of G protein alpha subunits in normal rat colon and in azoxymethane-induced colonic neoplasms.
Gastroenterology - 1 Dec 1998
Bolt M J, Mailloux R J, Rasenick M M, Wali R K, Skarosi S, Bissonnette M, Brasitus T A, Sitrin M D
Abstract excerpt
BACKGROUND & AIMS: Heterotrimeric G proteins are important in growth-regulating signal transduction. The aim of this study was to characterize the relative expression of G protein alpha subunits in rat colonocytes, colonocyte antipodal plasma membranes, and colonic neoplasms. METHODS: Antipodal plasma membranes were prepared from isolated colonocytes. Azoxymethane was administered to rats to induce colonic...
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