Expression of G protein alpha subunits in normal rat colon and in azoxymethane-induced colonic neoplasms.

doi:10.1016/s0016-5085(98)70028-9

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Article

Expression of G protein alpha subunits in normal rat colon and in azoxymethane-induced colonic neoplasms.

Gastroenterology - 1 Dec 1998

Bolt M J, Mailloux R J, Rasenick M M, Wali R K, Skarosi S, Bissonnette M, Brasitus T A, Sitrin M D

Abstract excerpt

BACKGROUND & AIMS: Heterotrimeric G proteins are important in growth-regulating signal transduction. The aim of this study was to characterize the relative expression of G protein alpha subunits in rat colonocytes, colonocyte antipodal plasma membranes, and colonic neoplasms. METHODS: Antipodal p...

Topics

Animals
Azoxymethane
Colon
Colonic Neoplasms
GTP-Binding Proteins
Genes, ras
Male
Mutation
Rats
Rats, Sprague-Dawley

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