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Article

Host genetic determinants of vaccine-induced eosinophilia during respiratory syncytial virus infection.

Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 1998

Hussell T, Georgiou A, Sparer T E, Matthews S, Pala P, Openshaw P J

Abstract excerpt

In BALB/c mice, sensitization with the attachment protein (G) of respiratory syncytial virus (RSV) leads to CD4+ T cell-mediated lung eosinophilia during subsequent challenge with RSV. To determine the host genetic influences on this model of lung eosinophilia, we tested 15 different inbred mouse strains. Eosinophilia developed in all H-2d (BALB/c, DBA/2n, and B10.D2), but not in H-2k (CBA/Ca, CBA/J, C3H, BALB.K,...

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PMID: 9834108

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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