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Article

Genetic background determines susceptibility to experimental immune-mediated blepharoconjunctivitis: comparison of Balb/c and C57BL/6 mice.

Experimental eye research - 1 Feb 2006

Fukushima Atsuki, Yamaguchi Tomoko, Ishida Waka, Fukata Kazuyo, Taniguchi Taketoshi, Liu Fu-Tong, Ueno Hisayuki

Abstract excerpt

Balb/c and C57BL/6 mice have been reported to be biased towards Th2 and Th1 immune responses, respectively. We investigated which strain is more susceptible to the development of experimental immune-mediated blepharoconjunctivitis (EC), which is predominantly mediated by Th2 immune responses. EC was induced by three different methods in Balb/c and C57BL/6 mice using ragweed (RW) as the antigen. The mice were thus...

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PMID: 16102751
DOI: 10.1016/j.exer.2005.06.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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