Article
Influence of the route of allergen administration and genetic background on the murine allergic pulmonary response.
American journal of respiratory and critical care medicine - 1 Feb 1997
Zhang Y, Lamm W J, Albert R K, Chi E Y, Henderson W R, Lewis D B
Abstract excerpt
We used various ovalbumin sensitization and challenge protocols to determine the importance of the route of allergen administration and the genetic background in modulating the physiologic, inflammatory, and immunologic features characteristic of allergen-induced asthma. In BALB/c mice, induction of maximal airway hyperresponsiveness and airspace eosinophilia required administration of ovalbumin by both the...
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