Article
Host genetic background and the innate inflammatory response of lung to influenza virus.
Microbes and infection - 1 Jan 2012
Trammell Rita A, Liberati Teresa A, Toth Linda A
Abstract excerpt
Many studies of influenza severity have focused on viral properties that confer virulence, whereas the contributory role of the host genetic background on infection severity remains largely unexplored. In this study, we measure the impact of inoculation with influenza virus in four strains of inbred mice - BALB/cByJ, C57BL/6J, A/J, and DBA/2J. To evaluate the extent to which responses are inherent to lung per se,...
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