Article
Respiratory syncytial virus-induced acute and chronic airway disease is independent of genetic background: an experimental murine model.
Virology journal - 25 May 2005
Chávez-Bueno Susana, Mejías Asunción, Gómez Ana M, Olsen Kurt D, Ríos Ana M, Fonseca-Aten Mónica, Ramilo Octavio, Jafri Hasan S
Abstract excerpt
BACKGROUND: Respiratory syncytial virus (RSV) is the leading respiratory viral pathogen in young children worldwide. RSV disease is associated with acute airway obstruction (AO), long-term airway hyperresponsiveness (AHR), and chronic lung inflammation. Using two different mouse strains, this study was designed to determine whether RSV disease patterns are host-dependent. C57BL/6 and BALB/c mice were inoculated...
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