Article
Apolipoprotein E allelic influence on human cerebrospinal fluid apolipoproteins.
Journal of lipid research - 1 Dec 1998
Montine K S, Bassett C N, Ou J J, Markesbery W R, Swift L L, Montine T J
Abstract excerpt
The major apolipoproteins (apo) on human cerebrospinal fluid lipoproteins are apoA-I and apoE. Given the association between inheritance of the varepsilon4 allele of the apoE gene (APOE4) and increased susceptibility to Alzheimer's disease, we tested the hypothesis that cerebrospinal fluid apolipoproteins may be influenced by APOE genotype and Alzheimer's disease. Lipoprotein fractions (d < 1.210 g/ml) were...
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