Article
Structure and functions of human cerebrospinal fluid lipoproteins from individuals of different APOE genotypes.
Experimental neurology - 1 Jan 1998
Rebeck G W, Alonzo N C, Berezovska O, Harr S D, Knowles R B, Growdon J H, Hyman B T, Mendez A J
Abstract excerpt
Recent data have implicated apolipoprotein E (apoE) in neuritic outgrowth, synaptic stability, and Alzheimer's disease; these data led us to examine the normal role of apoE-containing lipoproteins in the central nervous system (CNS). We isolated lipoproteins from human cerebrospinal fluid (CSF) in order to examine their composition and potential functions. CSF particles were composed of approximately one-third...
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