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Article

Apolipoprotein E levels in the cerebrospinal fluid of north Indian patients with Alzheimer's disease.

American journal of Alzheimer's disease and other dementias - 1 May 2013

Kandimalla Ramesh J L, Wani Willayat Yousuf, Anand R, Kaushal Alka, Prabhakar Sudesh, Grover Vinod K, Bharadwaj Neerja, Jain Kajal, Gill Kiran Dip

Abstract excerpt

The etiology of Alzheimer's disease (AD) is multifactorial involving both genetic and environmental factors. Apolipoprotein E (ApoE) gene plays a pivotal role in risk and age of onset of AD. Although it is broadly accepted that ApoE genotype is linked to the pathogenesis of AD, there are still controversial results regarding the association of ApoE levels in cerebrospinal fluid (CSF) with the occurrence of AD....

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PMID: 23612909
DOI: 10.1177/1533317513481097
PMCID: PMC10852682

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