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Article

Detection of apolipoprotein E phenotype in unconcentrated cerebrospinal fluid.

Journal of clinical laboratory analysis - 1 Jan 2003

Mehta P D, Patrick B A, Pirttila T, Coyle P K, Aisen P S

Abstract excerpt

We developed a simple method to detect apolipoprotein E (Apo E) polymorphism distribution in approximately 20 microL of unconcentrated cerebrospinal fluid (CSF). A combination of isoelectric focusing in 3 M urea gel and immunoblotting was employed. Apo E phenotypes were identified in CSF samples from 45 patients with probable Alzheimer disease (AD), 15 with multiple sclerosis (MS), and 25 with other neurological...

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Identifiers

PMID: 12526018
DOI: 10.1002/jcla.10063
PMCID: PMC6807740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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