Article
Absence of an apolipoprotein E epsilon4 allele is associated with increased parietal regional cerebral blood flow asymmetry in Alzheimer disease.
Archives of neurology - 1 Nov 1998
van Dyck C H, Gelernter J, MacAvoy M G, Avery R A, Criden M, Okereke O, Varma P, Seibyl J P, Hoffer P B
Abstract excerpt
BACKGROUND: The apolipoprotein E (Apo E) epsilon4 allele has been associated with parietal metabolic abnormalities and asymmetries in asymptomatic subjects at risk for Alzheimer disease (AD). However, previous research has shown minimal effect of the epsilon4 allele on regional cerebral blood flo...
Topics
- Age of Onset
- Aged
- Alleles
- Alzheimer Disease
- Analysis of Variance
- Apolipoproteins E
- Brain Mapping
- Case-Control Studies
- Cerebrovascular Circulation
- Female
- Genotype
- Humans
- Male
- Neuropsychological Tests
- Parietal Lobe