Article
No difference in cerebral glucose metabolism in patients with Alzheimer disease and differing apolipoprotein E genotypes.
Archives of neurology - 1 Mar 1997
Corder E H, Jelic V, Basun H, Lannfelt L, Valind S, Winblad B, Nordberg A
Abstract excerpt
BACKGROUND: Recent findings of a reduced cerebral metabolic rate of glucose (CMRGlu) in at-risk relatives of patients with Alzheimer disease (AD) who carry the apolipoprotein E (APOE) epsilon 4 allele suggest a causative role for the E4 isoform in cognitive changes that lead to AD. It is not know...
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