Article
Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer disease.
JAMA - 1 Jan 2000
Small G W, Mazziotta J C, Collins M T, Baxter L R, Phelps M E, Mandelkern M A, Kaplan A, La Rue A, Adamson C F, Chang L
Abstract excerpt
OBJECTIVE: Cerebral parietal hypometabolism and left-right asymmetry occur early in the course of Alzheimer disease (AD), and the apolipoprotein E type 4 allele (APOE epsilon 4) is a risk factor for familial AD. To determine if APOE epsilon 4 is associated with lowered brain function in nondemented relatives at risk for familial AD, we studied 12 relatives with APOE epsilon 4 and 19 relatives without APOE epsilon...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.