Reversion of the neoplastic phenotype of human glioblastoma cells by connexin 43 (cx43).

Article

Reversion of the neoplastic phenotype of human glioblastoma cells by connexin 43 (cx43).

Cancer research - 15 Nov 1998

Huang R P, Fan Y, Hossain M Z, Peng A, Zeng Z L, Boynton A L

Abstract excerpt

Connexins (cx), structural components of gap junction, are believed to play a role in the regulation of cell proliferation and suppression of the neoplastic phenotype. We used human brain glioblastoma tumor cells as a model system to test this hypothesis. Western blot and reverse transcription-PC...

Topics

Animals
Brain Neoplasms
Cell Communication
Cell Division
Connexin 43
Gap Junctions
Genes, Tumor Suppressor
Glioblastoma
Humans
Mice
Mice, Inbred BALB C
Mice, Nude
Phenotype
Transfection
Tumor Cells, Cultured

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