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Article

Immortalized connexin43 knockout cell lines display a subset of biological properties associated with the transformed phenotype.

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Sept 1997

Martyn K D, Kurata W E, Warn-Cramer B J, Burt J M, TenBroek E, Lau A F

Abstract excerpt

Immortalized cells from embryonic connexin43 knockout mice (Cx43-/-) and homozygous littermates (Cx43+/+) were cloned and characterized to determine whether the absence of Cx43 function would induce observable phenotypic changes. Cells of the Cx43+/+ clones expressed Cx43 and engaged in gap junctional communication with 10-12 neighboring cells. The Cx43-/- cells were devoid of Cx43 and communicated to less than 1...

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PMID: 9300183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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