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Article

Protein and messenger RNA expression of connexin43 in astrocytomas: implications in brain tumor gene therapy

1 May 1996

Abstract excerpt

The expression of connexin43, the primary gap-junction constituent of glial cells, was evaluated at the messenger RNA and protein levels in different grades of astrocytoma to investigate the relevance of gap junctions in herpes simplex virus-thymidine kinase (HSV-tk)-mediated gene therapy of brain tumors. Transduction of the retroviral-mediated HSV-tk gene into tumor cells with subsequent administration of...

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Identifiers

PMID: 8622159
DOI: 10.3171/jns.1996.84.5.0839

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Protein and messenger RNA expression of connexin43 in astrocytomas: implications in brain tumor gene therapyPMID 8622159Read ↗

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