Article
Asymptomatic deficiency in the peptide transporter associated to antigen processing (TAP).
Clinical and experimental immunology - 1 Jun 2002
de la Salle H, Saulquin X, Mansour I, Klayme S, Fricker D, Zimmer J, Cazenave J-P, Hanau D, Bonneville M, Houssaint E, Lefranc G, Naman R
Abstract excerpt
Human HLA class I deficiency is a rare disease which, in most of the patients described to date, results from a defect in subunit 1 or 2 of the peptide transporter associated with antigen processing (TAP). The clinical features of TAP deficiency include a chronic inflammation of the respiratory tract and/or granulomatous skin lesions. In this report, we describe two adult siblings with an HLA class I deficiency....
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