Article
Microsatellite instability in squamous cell carcinomas of the head and neck related to field cancerization phenomena.
British journal of cancer - 1 Nov 1998
Piccinin S, Gasparotto D, Vukosavljevic T, Barzan L, Sulfaro S, Maestro R, Boiocchi M
Abstract excerpt
Patients affected by squamous cell carcinoma of the head and neck (HNSCC) show frequent occurrence of multiple cancers and widespread precancerous lesions in the mucosa of the upper respiratory tract, a phenomenon known as field cancerization. In this study, we investigated the role of genetic in...
Topics
- Alleles
- Carcinoma, Squamous Cell
- Chromosomes, Human, Pair 3
- DNA, Neoplasm
- Female
- Head and Neck Neoplasms
- Humans
- Loss of Heterozygosity
- Male
- Microsatellite Repeats
- Middle Aged
- Neoplasms, Multiple Primary