Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microsatellite instability in squamous cell carcinomas of the head and neck related to field cancerization phenomena.

British journal of cancer - 1 Nov 1998

Piccinin S, Gasparotto D, Vukosavljevic T, Barzan L, Sulfaro S, Maestro R, Boiocchi M

Abstract excerpt

Patients affected by squamous cell carcinoma of the head and neck (HNSCC) show frequent occurrence of multiple cancers and widespread precancerous lesions in the mucosa of the upper respiratory tract, a phenomenon known as field cancerization. In this study, we investigated the role of genetic instability in the development of HNSCC and in particular in tumour multiplicity phenomena of the upper respiratory...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 3

Share to DNA, Neoplasm

Share to Head and Neck Neoplasms

Share to Loss of Heterozygosity

Share to Microsatellite Repeats

Share to Neoplasms, Multiple Primary

Source

Open in PubMed Open full text

Identifiers

PMID: 9820170
DOI: 10.1038/bjc.1998.644
PMCID: PMC2062986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microsatellite instability in squamous cell carcinomas of the head and neck related to field cancerization phenomena.PMID 9820170Read ↗

p53 Gene mutation and genetic instability in superficial multifocal esophageal squamous cell carcinoma.Semantic proximity Read ↗

Persistence of genetically altered fields in head and neck cancer patients: biological and clinical implications.Semantic proximity Read ↗

Molecular evidence of field cancerization in a patient with 7 tumors of the aerodigestive tract.Semantic proximity Read ↗

Multiple head and neck tumors frequently originate from a single preneoplastic lesion.Semantic proximity Read ↗

Multiple squamous cell carcinomas of the head and neck show different phenotypes of allelic loss patterns suggesting different clonal origin of carcinogenesis.Semantic proximity Read ↗

Risk factors for multiple malignancies in the head and neck.Semantic proximity Read ↗

Close correlation between mutations of E2F4 and hMSH3 genes in colorectal cancers with microsatellite instability.Semantic proximity Read ↗

A case-control study confirms that microsatellite assay can identify patients at risk of developing oral squamous cell carcinoma within a field of cancerization.Semantic proximity Read ↗

Mitochondrial C-tract alteration in premalignant lesions of the head and neck: a marker for progression and clonal proliferation.Semantic proximity Read ↗

Analysis for microsatellite instability and mutations of the DNA mismatch repair gene hMLH1 in familial gastric cancer.Semantic proximity Read ↗

Evidence for oligoclonality and tumor spread by intraluminal seeding in multifocal urothelial carcinomas of the upper and lower urinary tract.Semantic proximity Read ↗

p53 mutation profiling of multiple esophageal carcinoma using laser capture microdissection to demonstrate field carcinogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.