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Article

Multiple head and neck tumors frequently originate from a single preneoplastic lesion.

The American journal of pathology - 1 Sept 2002

Tabor Maarten P, Brakenhoff Ruud H, Ruijter-Schippers Henrique J, Van Der Wal Jacqueline E, Snow Gordon B, Leemans C René, Braakhuis Boudewijn J M

Abstract excerpt

The development of second primary tumors has a negative impact on the prognosis of head and neck squamous cell carcinoma. Previously, we detected genetically altered and tumor-related mucosal lesions in the resection margins in 25% of unselected head and neck squamous cell carcinoma patients (Tabor MP, Brakenhoff RH, van Houten VMM, Kummer JA, Snel MHJ, Snijders PJF, Snow GB, Leemans CR, Braakhuis BJM:...

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Identifiers

PMID: 12213734
DOI: 10.1016/S0002-9440(10)64266-6
PMCID: PMC1867244

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