Article
Somatic mutations in the RET protooncogene in Japanese and Chinese sporadic medullary thyroid carcinomas.
Japanese journal of cancer research : Gann - 1 Sept 1998
Shan L, Nakamura M, Nakamura Y, Utsunomiya H, Shou N, Jiang X, Jing X, Yokoi T, Kakudo K
Abstract excerpt
Despite advances in the understanding of the genotype-phenotype correlation in multiple endocrine neoplasia type 2A and 2B (multiple endocrine neoplasia (MEN) 2A, MEN 2B), and familial medullary thyroid carcinoma (FMTC), the frequency and prognostic relevance of RET protooncogene mutations in spo...
Topics
- Carcinoma, Medullary
- China
- Drosophila Proteins
- Gene Frequency
- Humans
- Japan
- Mutation
- Point Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Prognosis
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-ret
- Receptor Protein-Tyrosine Kinases