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Article

A single missense mutation in codon 918 of the RET proto-oncogene in sporadic medullary thyroid carcinomas.

Endocrine journal - 1 Apr 1995

Maeda S, Namba H, Takamura N, Tanigawa K, Takahashi M, Noguchi S, Nagataki S, Kanematsu T, Yamashita S

Abstract excerpt

The RET proto-oncogene is expressed in human medullary thyroid carcinoma and pheochromocytoma. Recently germline mutations of the RET proto-oncogene were reported in four syndromes (MEN 2A, MEN 2B, familial medullary thyroid carcinoma and Hirschprung's disease) and somatic mutation was also found in sporadic medullary thyroid carcinoma. To determine the incidence of RET mutations in medullary thyroid carcinoma in...

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Identifiers

PMID: 7627269
DOI: 10.1507/endocrj.42.245

Genes

RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A single missense mutation in codon 918 of the RET proto-oncogene in sporadic medullary thyroid carcinomas.PMID 7627269Read ↗

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Mutations of codon 918 in the RET proto-oncogene correlate to poor prognosis in sporadic medullary thyroid carcinomasSemantic proximity Read ↗

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Somatic mutations in RET exons 12 and 15 in sporadic medullary thyroid carcinomas: different spectrum of mutations in sporadic type from hereditary type.Semantic proximity Read ↗

Three novel mutations in the RET proto-oncogene.Semantic proximity Read ↗

Mutations of codon 918 in the RET proto-oncogene correlate to poor prognosis in sporadic medullary thyroid carcinomas.Semantic proximity Read ↗

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