Article
Low-grade pulmonary mucosa-associated lymphoid tissue lymphoma with or without intraclonal variation.
American journal of respiratory and critical care medicine - 1 Nov 1998
Kurosu K, Yumoto N, Furukawa M, Kuriyama T, Mikata A
Abstract excerpt
We examined the immunoglobulin heavy chain variable (Ig VH) region genes of 11 low-grade pulmonary mucosa-associated lymphoid tissue (MALT) lymphomas by a two-step polymerase chain reaction (PCR) and sequencing analysis. We observed frequent somatic mutations with the positive selective pressure...
Topics
- Adult
- Aged
- Aged, 80 and over
- Agglutinins
- Antibodies, Antinuclear
- Autoantibodies
- B-Lymphocytes
- Clone Cells
- Cryoglobulins
- Female
- Gene Rearrangement
- Genes, Immunoglobulin
- Genetic Predisposition to Disease
- Genetic Variation
- Germinal Center
- Hemagglutinins
- Humans
- Immunoglobulin Heavy Chains