Article
Pattern of gene alterations in intraductal breast neoplasms associated with histological type and grade.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 1995
Tsuda H, Fukutomi T, Hirohashi S
Abstract excerpt
To reveal any association between the histological type and grade of intraductal breast neoplasms and the manner of accumulation of gene alterations, eight types of gene alterations, i.e., loss of heterozygosity (LOH) on chromosomal arms 16p, 16q, 17p, 17q, and 18q, amplification of the c-erbB-2...
Topics
- Breast Neoplasms
- Carcinoma, Intraductal, Noninfiltrating
- Chromosome Mapping
- Chromosomes, Human, Pair 16
- Chromosomes, Human, Pair 17
- Chromosomes, Human, Pair 18
- DNA Probes
- Female
- Fibroblast Growth Factor 3
- Fibroblast Growth Factor 4
- Fibroblast Growth Factors
- Gene Amplification
- Genes, erbB-2
- Genes, p53
- Genetic Markers
- Humans
- Loss of Heterozygosity
- Mutation