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Article

Genetic alterations on chromosome 16 and 17 are important features of ductal carcinoma in situ of the breast and are associated with histologic type.

British journal of cancer - 1 Dec 1999

Vos C B, ter Haar N T, Rosenberg C, Peterse J L, Cleton-Jansen A M, Cornelisse C J, van de Vijver M J

Abstract excerpt

We analysed the involvement of known and putative tumour suppressor- and oncogene loci in ductal carcinoma in situ (DCIS) by microsatellite analysis (LOH), Southern blotting and comparative genomic hybridization (CGH). A total of 78 pure DCIS cases, classified histologically as well, intermediately and poorly differentiated, were examined for LOH with 76 markers dispersed along all chromosome arms. LOH on...

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Identifiers

PMID: 10604741
DOI: 10.1038/sj.bjc.6693372
PMCID: PMC2362977

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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