Article
Genetic progression, histological grade, and allelic loss in ductal carcinoma in situ of the breast.
Cancer research - 15 Nov 1996
Fujii H, Szumel R, Marsh C, Zhou W, Gabrielson E
Abstract excerpt
To investigate the relationships of specific allelic losses to progression and histological grade of ductal carcinoma in situ (DCIS) of the breast, we studied PCR-amplified microsatellite markers on ten chromosomal arms in 41 cases of DCIS without synchronous invasive cancer. For all chromosomal arms combined, the number of allelic losses was significantly greater in lesions of intermediate or high nuclear grade...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
