Article
Accumulation of Chromosomal Imbalances From Intraductal Proliferative Lesions to Adjacent In Situ and Invasive Ductal Breast Cancer
1 Mar 2000
Abstract excerpt
Carcinoma of the breast is thought to evolve through a sequential progression from normal to proliferative epithelium and eventually into carcinoma. Here lumpectomy specimens from five patients were studied, selected for the presence of ductal hyperplasia without atypia, atypical ductal hyperplasia, ductal carcinoma in situ, and invasive ductal carcinoma. Laser microdissection of tissue allowed precise sampling...
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