Allelic loss on chromosome 13q in human prostate carcinoma.

Article

Allelic loss on chromosome 13q in human prostate carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 1997

Melamed J, Einhorn J M, Ittmann M M

Abstract excerpt

To clarify the role in prostate tumorigenesis played by loss of the three known or putative tumor suppressor loci on the centromeric portion of chromosome 13q, we examined 80 clinically localized and 15 advanced prostate carcinomas for allelic loss at microsatellite markers mapped to this region,...

Topics

Alleles
BRCA2 Protein
Carcinoma
Chromosomes, Human, Pair 13
Genes, Retinoblastoma
Genes, Tumor Suppressor
Humans
Loss of Heterozygosity
Male
Neoplasm Proteins
Prostatic Neoplasms
Transcription Factors

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.