Distinct regions of allelic loss on 13q in prostate cancer.

Article

Distinct regions of allelic loss on 13q in prostate cancer.

Cancer research - 1 Mar 1996

Cooney K A, Wetzel J C, Merajver S D, Macoska J A, Singleton T P, Wojno K J

Abstract excerpt

Loss of heterozygosity (LOH) involving the long arm of chromosome 13 has been reported to occur in as many as one third of primary prostate cancers. Candidate tumor suppressor genes on 13q that may be important in the development of prostate cancer include the retinoblastoma susceptibility gene (...

Topics

Aged
Alleles
Chromosome Mapping
Chromosomes, Human, Pair 13
Gene Deletion
Genetic Markers
Humans
Male
Middle Aged
Prostatic Neoplasms

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.