Article
Distinct regions of allelic loss on 13q in prostate cancer.
Cancer research - 1 Mar 1996
Cooney K A, Wetzel J C, Merajver S D, Macoska J A, Singleton T P, Wojno K J
Abstract excerpt
Loss of heterozygosity (LOH) involving the long arm of chromosome 13 has been reported to occur in as many as one third of primary prostate cancers. Candidate tumor suppressor genes on 13q that may be important in the development of prostate cancer include the retinoblastoma susceptibility gene (RBI) and a gene associated with inherited breast cancer (BRCA2). To define the pattern of allelic loss of 13q in...
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