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Article

Loss of heterozygosity at 13q14 and 13q21 in high grade, high stage prostate cancer

25 Oct 2001

Abstract excerpt

BACKGROUND: Loss of heterozygosity (LOH) at chromosome 13q has been frequently detected in prostate cancer, and three regions (i.e., 13q14, 13q21, and 13q33) may harbor tumor suppressor genes important in this neoplasm. In this study, we examined the frequency of 13q LOH in advanced prostate cancers, in order to determine the clinicopathologic relevance of 13q LOH. METHODS: LOH was determined by analyzing...

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PMID: 11746261
DOI: 10.1002/pros.1131

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