Allelic losses at loci on chromosome 10 are associated with metastasis and progression of human prostate cancer.

doi:10.1002/(SICI)1098-2264(199612)17:4<245::AID-GCC6>3.0.CO;2-3

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Article

Allelic losses at loci on chromosome 10 are associated with metastasis and progression of human prostate cancer.

Genes, chromosomes & cancer - 1 Dec 1996

Komiya A, Suzuki H, Ueda T, Yatani R, Emi M, Ito H, Shimazaki J

Abstract excerpt

DNA samples from tumors and paired normal tissues from 48 patients with prostate cancer (stage B, 16 cases; stage C, 14 cases; stage D, 18 cases) were examined with 26 polymorphic markers spanning chromosome 10. Allelic losses were observed in 17 of the 46 cases (37%) that were informative with a...

Topics

Adenocarcinoma
Alleles
Chromosome Banding
Chromosomes, Human, Pair 10
Heterozygote
Humans
Liver Neoplasms
Male
Neoplasm Metastasis
Prostatic Neoplasms
Sequence Deletion

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