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Article

Genetic variation of HIV type 1: relevance of interclade variation to vaccine development.

AIDS research and human retroviruses - 1 Oct 1998

van der Groen G, Nyambi P N, Beirnaert E, Davis D, Fransen K, Heyndrickx L, Ondoa P, Van der Auwera G, Janssens W

Abstract excerpt

Accumulating data in human immunodeficiency virus (HIV)-infected individuals support the hypothesis that in primary human immunodeficiency virus type 1 (HIV-1) isolates of different clades and phenotype (syncytium inducing [SI] and nonsyncytium inducing [NSI]) common antigenic structures must exist that can stimulate the immune response to produce a broad spectrum (cross-clade and cross SI and NSI) neutralization...

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PMID: 9814946

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