Article
Two antigenically distinct subtypes of human immunodeficiency virus type 1: viral genotype predicts neutralization serotype.
The Journal of infectious diseases - 1 Jan 1994
Mascola J R, Louwagie J, McCutchan F E, Fischer C L, Hegerich P A, Wagner K F, Fowler A K, McNeil J G, Burke D S
Abstract excerpt
At least five distinct genetic subtypes (genotypes) of human immunodeficiency virus type 1 (HIV-1) have been identified by DNA sequencing. Current vaccine candidates are based on virus strains from North America and Europe that represent only one subtype. The extent to which distinct genotypes of HIV-1 correspond to antigenically distinguishable serotypes is largely unknown and may be critically important to...
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