Article
Genetic variation of HIV type 1 in four World Health Organization-sponsored vaccine evaluation sites: generation of functional envelope (glycoprotein 160) clones representative of sequence subtypes A, B, C, and E. WHO Network for HIV Isolation and Characterization.
AIDS research and human retroviruses - 1 Nov 1994
Gao F, Yue L, Craig S, Thornton C L, Robertson D L, McCutchan F E, Bradac J A, Sharp P M, Hahn B H
Abstract excerpt
As part of the WHO Network for HIV Isolation and Characterization, we PCR amplified, cloned, and sequenced gp120 and gp160 genes from 12 HIV-1 isolates collected in four WHO-sponsored vaccine evaluation sites (Brazil, Rwanda, Thailand, Uganda). Envelope clones were derived from PBMC-grown isolate...
Topics
- AIDS Vaccines
- Amino Acid Sequence
- Base Sequence
- Brazil
- Cloning, Molecular
- DNA Primers
- DNA, Viral
- Gene Products, env
- Genetic Variation
- HIV Envelope Protein gp120
- HIV Envelope Protein gp160
- HIV Infections
- HIV-1