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Article

Analysis of the mesotelencephalic dopamine system by quantitative-trait locus introgression.

Neurochemical research - 1 Nov 1998

Vadasz C, Sziraki I, Sasvari M, Kabai P, Murthy L R, Saito M, Laszlovszky I

Abstract excerpt

One of the significant factors that affect brain dopamine function is the activity of tyrosine hydroxylase (TH), the first and rate-limiting enzyme in catecholamine biosynthesis. For the analysis of the genetically determined role of dopamine function and TH in behavior and in the regulatory mechanisms of the mesotelencephalic dopamine system we devised a novel genetic strategy (Vadasz; Mouse Genome 88:16-18;...

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Identifiers

PMID: 9814544
DOI: 10.1023/a:1020790320875

Genes

TH

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