Article
Quantitative trait loci affecting methamphetamine responses in BXD recombinant inbred mouse strains.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Jan 1997
Grisel J E, Belknap J K, O'Toole L A, Helms M L, Wenger C D, Crabbe J C
Abstract excerpt
Individual differences in most behavioral and pharmacological responses to abused drugs are dependent on both genetic and environmental factors. The genetic influences on the complex phenotypes related to drug abuse have been difficult to study using classical genetic analyses. Quantitative trait...
Topics
- Alleles
- Animals
- Behavior, Animal
- Body Temperature Regulation
- Brain Chemistry
- Central Nervous System Stimulants
- Chromosome Mapping
- Crosses, Genetic
- Dose-Response Relationship, Drug
- Female
- Male
- Mastication
- Methamphetamine
- Mice
- Mice, Inbred C57BL