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Article

The AMPA receptor subunit GluR-B in its Q/R site-unedited form is not essential for brain development and function.

Proceedings of the National Academy of Sciences of the United States of America - 10 Nov 1998

Kask K, Zamanillo D, Rozov A, Burnashev N, Sprengel R, Seeburg P H

Abstract excerpt

Calcium permeability of L-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs) in excitatory neurons of the mammalian brain is prevented by coassembly of the GluR-B subunit, which carries an arginine (R) residue at a critical site of the channel pore. The codon for this arginine is created by site-selective adenosine deamination of an exonic glutamine (Q) codon at the pre-mRNA level. Thus,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 9811877
DOI: 10.1073/pnas.95.23.13777
PMCID: PMC24896

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Source receipt: pubmed, retrieved 7 Sept 2026.

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The AMPA receptor subunit GluR-B in its Q/R site-unedited form is not essential for brain development and function.PMID 9811877Read ↗

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